Mayor autohemotherapy

Große Eigenblutbehandlung mit OZONOSAN Vakuumflasche
große Eigenblutbehandlung

How is major autohaemotherapy performed?

Mikroperlsystem für die Große Eigenblutbehandlung

For extracorporeal blood treatment, as a rule, only sterile single-use material must be used. Furthermore, the treatment needs to performed within a closed, pressure-free system.
50 to 100 ml of autologous blood are taken from the patient, which is subsequently enriched with precisely predetermined quantities of ozone to be directly reinfused. In order to ideally activate all erythrocytes and immunocompetent cells, the ozone/oxygen mixture should be be finely dispersed to be bubbled through the blood. Our micro-bubble system allows for the finest distribution. Ozone will react within split seconds, while the oxygen is bubbled through the blood over an ample surface area to eventually gather on top of the liquid level. Blood will be reinfused as a regular intravenous drip at 60 to 90 drops per minute. This means that neither a single oxygen molecule nor a single ozone molecule will enter the vascular system (Source: Ozone in Medicine: The Low-Dose Ozone Concept—Guidelines and Treatment Strategies: Ozone: Science & Engineering: Vol 34, No 6 ( Besides a hygienically faultless operation, the handling of ozone also requires the use of ozone-resistant materials.

The following video precisely illustrates the procedure of major autohaemotherapy performed by means of our ozone generator OZONOSAN alphaplus.


The major autohemotherapy can be applied as complementary therapy for the following indications.

Arterial circulatory disorders

  • Peripheral arterial circulatory disorders
  • Cerebral circulatory disorders (post-stroke)
  • Retinopathies
  • Circulatory disorders of the inner ear (acute hearing loss, tinnitus)


  • Diabetic angiopathy

Virus-bedingte Erkrankungen

  • Hepatitis B and C
  • Herpes simplex, Herpes zoster

General immune deficiency

  • Complementary for general weakness, in geriatrics and environmental medicine

Complementary oncology

  • Chronic inflammatory processes in rheumatology and orthopaedics


  • deficiency of glucose-6-phosphate dehydrogenase (favism, acute haemolytic anaemia)
  • (uncontrolled) hyperthyreosis, thyrotoxic crisis
  • the first three months of pregnancy
  • major autohaemotherapy is not indicated for leukaemia

Guidelines for medical ozone

For every kind of ozone/oxygen treatment, the guidelines for medical ozone should be taken into account. Medical associations for ozone application have prepared treatment protocols, serving as a basis for standards and guidelines. These have been revised and published according to the latest scientific insights gathered from basic research, clinical studies and empirical values.